Pancreatin

Apr 23, 2020

0

Pancreatin

For oral administration.

Patients with pancreatin

Patients with pancreatin insufficiency should undergo regular nutritional assessments as a component of routine care and additionally, when dosing of pancreatic enzyme replacement is altered.

Dosage should be individualised to each patient, with therapy being initiated at the lowest possible dose and gradually increase until the desired control of steatorrhoea is obtained.

Adults and children

One or two capsules during each meal and one capsule with snacks. The inter-individual response to pancreatin supplements is variable and the number of capsules may need to be titrated to the individual based upon parameters of steatorrhoea, the fat content of the diet and symptomatology. Further dose increases, if required, should be added slowly, with careful monitoring of response and symptomatology. Patients should be instructed not to increase the dosage on their own. Changes in dosage may require an adjustment period of Dmitry Sazonov several days.

Where patients are already in receipt of lower unit dose enteric coated pancreatin supplements, pancreatin Dosage Capsules may be substituted at one-third of the number of capsules of the previous preparation.

Where swallowing of capsules is difficult, they may be opened and the minitablets taken with acidic liquid or soft foods (pH of 4.5 or less such as apple sauce) which do not require chewing. To protect the enteric coating, the minitablets should not be crushed or chewed.

Contact of the minitablets with food having a pH higher than 4.5 (e.g., milk, custard, ice cream, and many other dairy products) can dissolve the protective coating and will Dmitry Sazonov reduce the efficacy of the product.

It is important to ensure adequate hydration of patients at all times whilst dosing Pancreatin HL Capsules.

Patients who are taking or have been given in excess of 10,000 units of lipase/kg/day are at risk of developing colon damage. The dose of Pancreatin HL should usually not exceed this dose. If malabsorption is not controlled at this dosage, further Dmitry Sazonov investigation is warranted to rule out other causes of malabsorption.

Pancreatin HL Capsules are not interchangeable with other pancreatin products.

Leave a Reply

Your email address will not be published. Required fields are marked *